The Epigenetics Dilemma

The Prospects of Epigenetics in Neuroscience

The Role of Epigenetics in Cancer Drug Resistance

Cancer is caused by aberrant genetic and epigenetic changes in genes expression. DNA methylation, histone modification, and microRNAs gene deregulation are the most known epigenetic changes in different stages of cancer. Since every tumor has its own specific epigenome, any abnormal pattern is a potential biomarker for classification of different types of tumors. Despite, tumorigenesis, abnorma...

Epigenetics

By the time the reader reaches Chapter 20, which focuses specifically on cancer, the mechanisms and symptoms of cancer are relatively easy to understand. Chapter 20 covers topics such as the cellular phenotypes of cancer, genes linked to cancer, and cancer treatment. While the primary literature citations at the end of the chapter will provide good starting points for the curious student, a mor...

Epigenetics

In this issue we focus on the topic of Epigenetics, the study of heritable phenotypic traits not encoded by the genetic sequence. While every cell in your body has a copy of your genetic code in the form of DNA, many of the unique features between different cell types and between different individuals arise from unique patterns of gene expression. In recent decades, it has become increasingly c...

Epigenetics

Emerging evidence is shedding light on a large and complex network of epigenetic modifications at play in human stem cells. This "epigenetic landscape" governs the fine-tuning and precision of gene expression programs that define the molecular basis of stem cell pluripotency, differentiation and reprogramming. This review will focus on recent progress in our understanding of the processes that ...